Kisspeptin-10
Kisspeptin-10, a decapeptide and member of the kisspeptin family, is integral to the regulation of reproductive functions, including puberty and fertility control. Derived from the larger precursor protein, kisspeptin-54, it comprises 10 amino acids and plays a pivotal role in the hypothalamic-pituitary-gonadal (HPG) axis, a crucial pathway for reproductive hormone control.
Studies indicate that kisspeptin-10 stimulates the release of gonadotropin-releasing hormone (GnRH), subsequently triggering the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are vital for reproductive organ maturation and cycle regulation.
Overall, kisspeptin-10 is a key component in the intricate network of hormonal signals governing reproductive processes. Ongoing research on kisspeptins and their receptors continues to enhance our understanding of reproductive physiology and explore potential therapeutic avenues.
Clinical studies have demonstrated that Kisspeptin-10 increases luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone levels in men. Additionally, the peptide has been shown to stimulate gonadotropin release in women during the pre-ovulatory phase of the menstrual cycle.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232613/
Kisspeptin |
|
CAS Number |
374675-21-5 |
Molar Mass |
1302.45 g/mol |
Chemical Formula |
C63H83N17O14 |
Sequence |
H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
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