Follistatin 344 – 1mg

Follistatin 344 is a recombinant, high‑purity peptide widely studied for its role in inhibiting myostatin—a negative regulator of muscle growth. As a result, it has gained strong interest in scientific research focused on skeletal muscle hypertrophy, injury recovery, and age‑related muscle wasting (sarcopenia).

Derived from the full‑length human sequence, Follistatin 344 functions as a binding protein within the TGF‑β superfamily, neutralising not only myostatin but also activin A and other regulatory peptides. Its indirect pathway—bypassing the androgen receptor—makes it a compelling target for research into non‑hormonal muscle enhancement.

Key Research Applications

Follistatin 344 has been studied across various biological systems for its potential to:

• Increase lean muscle mass without hormonal stimulation
• Enhance muscle fibre regeneration following injury or surgical trauma
• Reduce inflammation via modulation of cytokine activity
• Support connective tissue and tendon recovery
• Counteract catabolic muscle loss in disease models
• Modulate fertility and reproductive signalling pathways

Its effectiveness as a myostatin inhibitor positions Follistatin 344 at the centre of regenerative biology and muscle therapeutics research.

Mechanism of Action

Follistatin 344 acts by binding and neutralising circulating levels of myostatin and related proteins such as activin A, preventing their interaction with ActRIIB receptors. This reduces the downstream signalling responsible for inhibiting muscle development. Additionally, Follistatin has shown potential to influence folliculogenesis, cell differentiation, and immune regulation, highlighting its broad research relevance.

Important Availability Notice

Please note: Pre‑Mixed Cartridges are only available for delivery within Spain, France, and Portugal, where we maintain strict cold‑chain shipping to guarantee product integrity. For all other regions, we recommend selecting Lyophilised Cartridges, which can be shipped safely without refrigeration.

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